Well, based on a lot of frustrated posts on the DC Forum, a lot of SP and MP gamers have had problems running PK on laptops with integrated graphics cards (namely Intel). The reason for this is that Intel do not support T&L (transform and lighting) required for many DirectX games.
http://www.dreamcatchergames.com/forums/showthread.php?t=24937&highlight=intel
Since what PK requires is T&L hardware support, to get around this, all you need to do is emulate that support in software. Since it doesn

A tool exists for doing this; namely
Download it, unzip it (basically run it), then run the App (3DAnalyze.exe) and you should see something like this:

Firstly select the Painkiller.exe, then tick the
There are other options of running in a Window etc. but you can try those out for yourselves.